Dr. Alfredo Quiñones-Hinojosa
Neurosurgeon-Scientist · Co-Founder
A Breakthrough in Neuro-Oncology
Decades of research brought us here: a breakthrough treatment for patients with glioblastoma.
Dome Therapeutics is developing a first-in-class nanomedicine designed to destroy the residual brain cancer stem cells that drive tumor regrowth — the missing link in curing glioblastoma.
01 — The Need
For decades, glioblastoma care has had to focus on hope.
Patients and their loved ones need neurosurgeons, neurologists, scientists, and entrepreneurs to provide a treatment that will stop tumor regrowth — once and for all.
It is nearly guaranteed that glioblastoma will recur. Residual brain cancer stem cells, the source of tumor regrowth, survive every existing treatment. The key to stopping recurrence is destroying those stem cells.
No treatment exists that can do this — until now.
$0
Average per-patient lifetime cost of treatment
0 mo
Average life expectancy after diagnosis
0%
Of patients live 5 years after diagnosis
0+
Patients diagnosed with glioblastoma each year in the U.S.
02 — The Science
An innovative nanomedicine to prevent tumor regrowth.
By discovering a way to target brain cancer stem cells, we've created a fundamentally different approach — one that will positively transform patient outcomes.
- 01
Identify What to Target
Pinpoint brain cancer stem cells — the true source of tumor regrowth left behind by current treatments.
- 02
Discover What Stops Them
Uncover the molecular mechanisms that render brain cancer stem cells vulnerable and can be therapeutically exploited.
- 03
Invent the Treatment
Engineer a novel therapeutic payload designed specifically to destroy residual brain cancer stem cells.
- 04
Design the Delivery
Build a proprietary nanomedicine platform that carries the treatment past the blood-brain barrier, precisely.
Our nanomedicine is a transformational breakthrough — the beginning of the next generation of stem cell and gene therapy to treat brain diseases.
Learn more about our platform03 — Our Platform
Built at Johns Hopkins. Driven by empathy.
For years, each of us dedicated our careers to brain cancer in our own way. Shared values of scientific excellence, patient-centered innovation, and empathy brought us together at Johns Hopkins — and created what is now Dome.
Our mission is to increase the life expectancy of patients with any brain disease, starting with a cure for glioblastoma.
Beyond therapeutic innovation, we proudly support the Mission:Brain Foundation — a global non-profit dedicated to providing neurosurgery care to underserved regions.
04 — The Team
Neurosurgeons, engineers, and strategists — united by a single mission.
Dr. Jordan J. Green
Biomedical Engineer · Co-Founder
Dr. Jim Kyung-Soo Liew
Finance & Strategy · Co-Founder
Contact
Partner with us to end glioblastoma.
Researchers, investors, patients, and advocates — reach out to learn how Dome is redefining brain cancer treatment.