Leadership
Dr. Alfredo Quiñones-Hinojosa
Neurosurgeon-Scientist · Co-Founder
Internationally recognized neurosurgeon, brain tumor researcher, and pioneer in glioblastoma stem cell biology whose research helps guide Dome Therapeutics' scientific direction.
Biography
Dr. Alfredo Quiñones-Hinojosa ("Dr. Q") is the William J. and Charles H. Mayo Professor, Chair of Neurologic Surgery, and Dean of Research at Mayo Clinic in Florida. His lab studies glioblastoma, brain cancer stem cells, and tumor invasion.
He has authored more than 500 peer-reviewed papers and holds multiple patents. At Dome, he leads scientific and clinical direction for the glioblastoma program.
Focus
Research Interests
- Glioblastoma biology
- Brain cancer stem cells
- Tumor invasion and recurrence
- Tumor microenvironment
- Translational neuro-oncology
- Awake brain mapping
- Neurosurgical oncology
Research
Selected Publications
- 2010
Oxygen in stem cell biology: A critical component of the stem cell niche
Cell Stem Cell
- 2009
Independent association of extent of resection with survival in patients with malignant brain astrocytoma
Journal of Neurosurgery
- 2006
Cellular composition and cytoarchitecture of the adult human subventricular zone
Journal of Comparative Neurology
Training
Education
B.A., Psychology (Highest Honors)
University of California, Berkeley
M.D. (Cum Laude)
Harvard Medical School
Residency, Neurological Surgery
University of California, San Francisco
Postdoctoral Fellowship, Developmental & Stem Cell Biology
University of California, San Francisco
Recognition
Awards & Honors
Howard Hughes Medical Institute Physician–Scientist Award
Herbert W. Nickens Faculty Fellowship
Popular Science "Brilliant 10" Scientist
Ohtli Award (Government of Mexico)
America's Role Model Award (Olender Foundation)
Career
Professional Experience
- Present
Co-Founder
Dome Therapeutics
- Present
Chair, Department of Neurologic Surgery
Mayo Clinic
- Present
Dean of Research
Mayo Clinic Florida
- Present
William J. and Charles H. Mayo Professor
Mayo Clinic
- Previously
Professor of Neurosurgery, Oncology, Neurology, and Cellular & Molecular Medicine
Johns Hopkins University School of Medicine
- Previously
Director, Brain Tumor Stem Cell Biology Laboratory
Johns Hopkins University
Publications
Books
Becoming Dr. Q: My Journey from Migrant Farm Worker to Brain Surgeon
Core Techniques in Operative Neurosurgery
Schmidek & Sweet Operative Neurosurgical Techniques (Editor)
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